This site provides access to view the data from the Accelerating Medicines Partnership (AMP) SLE Phase I project.
To learn more about this project, please refer to our preprint paper available at bioRxiv: The immune cell landscape in kidneys of lupus nephritis patients
Please feel free to explore the site. On this site, we provide an interactive view of the single-cell RNA-seq data. To access the full data, please go to ImmPort.
Please contact us if you have any questions, requests, or comments on the analysis and results.
CM0: CD16+ machrophage, inflammatory; CM1: CD16+ macrophage, phagocytic; CM2: Tissue-resident macrophage; CM3: cDCs; CM4: CD16+ macrophage, M2-like;
CT0a: Effector memory CD4+ T cells; CT0b: Central memory CD4+ T cells; CT1: CD56_dim CD16+ NK cells; CT2: CTLs; CT3a: Tregs; CT3b: TFH-like cells; CT4: GZMK+ CD8+ T cells; CT5a: Resident memory CD8+ T cells; CT5b: CD56_bright CD16- NK cells; CT6: ISG-high CD4+ T cells
CB0: Activated B cells; CB1: Plasma cells/Plasmablasts; CB2a: Naive B cells; CB2b: pDCs; CB3: ISG-high B cells;
CD0: Dividing cells; CE0: Epithelial cells